WHAP is a statistical test for case/control association studies. It takes advantage of the known correlation structure between SNPs in the HapMap in order to improve power over traditional methods. The full details are described in Leveraging the HapMap Correlation Structure in Association Studies.

This server performs the weighted haplotype association (WHAP) test on moderately sized studies. It accepts as input a set of dbSNP rsids which are genotyped over a set of cases and controls. Plink is used to estimate Hardy-Weinberg equilibrium for quality control.

If you would like to run a wholge-genome data set on our cluster, or if you have questions, please contact Noah Zaitlen. This is the joint work of Zaitlen N, Kang H, Eskin E, Halperin E.

This web-site is based upon work supported by the National Science Foundation under Grant No. 0513599. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.